What is the principle behind chelation therapy?
The use of chelating substances that chemically bond with toxins, get carried and then excreted either in the urine or feces.
What is chelation therapy?
A therapy that uses ligating substances to chemically bond with toxic heavy metals, then get carried to the digestive system and excreted either in the urine or feces. An artificial amino acid is injected to work at molecular levels and effectively removes free radicals, long linked to cancer development.
What chelating agents are used?
Agents used vary accordingly to the disease being treated.
If, for example, one requires to detoxify from arsenic, BAL would be used. When iron detoxification is needed, Deferasirox has not only shown good results, but a good side effect profile. Still, the most common agent is EDTA since it can form a stable bond with several different metals.
How is the chelation therapy given?
It can be administered via IV, rectally and orally. EDTA is most commonly given via IV routes, Deferasirox on the other hand, is administered orally.
What dose will be used?
Dose applied is determined by body weight, the amount of traced metals and renal function. The latter because it has been found that with renal failure, the larger metal excretion increases the risk of nephrotoxicity (toxicity in the kidneys).
Could you provide studies that prove chelation therapy efficiency?
Of course! Chelation therapies have been long recognized as an optimum treatment of metal intoxications. You can have full access to a study published by the International Journal of Environmental Research and Public Health here.
There are several studies that have focused their attention on a specific metal detoxification, such as iron, zinc, lead and arsenic.